Intranuclear inclusions in multiple myeloma
نویسندگان
چکیده
منابع مشابه
Intranuclear inclusions in multiple myeloma and macroglobulinemia.
By GEOFFREY M. BiurriN, YASUKAZU TANAKA AND GEORGE Biuicim n M ANY DISTINCTIVE inclusion bodies have been described in the plasma cells of inflammatory and neoplastic diseases and in plasma cell tumors. Most of these structures have been in the cytoplasm of the plasma cell, and hematologists are familiar with Russell bodies,’ Mott cells,’ “grape cells,”2 “morula cells,”3 and crystalline precipi...
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A patient with plasma cell myeloma producing only Bence Jones lambda protein was found to have pale intranuclear inclusions in the majority of the bone marrow plasma cells. These inclusions, previously undescribed in myeloma patients producing only Bence Jones protein, contained Bence Jones lambda protein, were non-electron dense, bound by a single membrane, and contained no cytoplasmic structu...
متن کاملMultiple myeloma with numerous intranuclear Russell bodies.
Correspondence: A. Martín-Noya, M.D., Servicio de Hematología, Hospital Universitario Virgen del Rocío, Avda. Manuel Siurot s/n1, 41013 Seville, Spain. Phone: international +34-95-4248122 – Fax: international +34-954248124 – E-mail: [email protected] A71-year-old woman was admitted to hospital because of repeated episodes of epistaxis and an eight month history of fatigue and weight loss. On ph...
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A64 year old woman complaining of a long-lasting bone pain in the lumbar region was admitted to our Institute. Routine laboratory examination on admission disclosed: Hb 10.1 g/dL; RBC 3.3531012/L, WBC 5.93109/L, PTL 203109/L. Differential blood count showed occasional plasma cells with atypical features in the peripheral blood. Serum electrophoresis demonstrated a peak in the g region (56%) com...
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This literature review presents the most recent developments in the management of multiple myeloma, which is characterized by the presence of abnormal plasma cells (myeloma cells) that accumulate into the bone marrow. Aspects related to pathophysiology, clinical manifestations, laboratory, study and treatment are described. These pieces of information are necessary to accomplish a better ...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 1990
ISSN: 0361-8609,1096-8652
DOI: 10.1002/ajh.2830350418